Primary biliary cirrhosis (PBC) Primary sclerosing cholangitis (PSC)
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Impact of Microbes on the Pathogenesis of Primary Biliary Cirrhosis (PBC) and Primary Sclerosing Cholangitis (PSC)
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) represent the major clinical entities of chronic cholestatic liver diseases. Both disorders are characterized by portal inflammation and slowly progress to obliterative fibrosis and eventually liver cirrhosis. Although immune-pathogenic mechanisms have been implicated in the pathogenesis of PBC and PSC, neither disorder is...
متن کاملA patient with primary biliary cirrhosis and ulcerative colitis with progression to primary sclerosing cholangitis and colorectal cancer: A case report
Introduction: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon characterized by intermittent exacerbations and remissions. It can be associated with primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC) and complicated with colorectal cancer (CRC). We describe a complicated case of associaton of PBC and chronic UC, eventually progressed to PSC and CRC. Ca...
متن کاملThe relation between plasma tyrosine concentration and fatigue in primary biliary cirrhosis and primary sclerosing cholangitis
BACKGROUND In primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) fatigue is a major clinical problem. Abnormal amino acid (AA) patterns have been implicated in the development of fatigue in several non-hepatological conditions but for PBC and PSC no data are available. This study aimed to identify abnormalities in AA patterns and to define their relation with fatigue. ME...
متن کاملPrimary Biliary Cirrhosis and Primary Sclerosing Cholangitis: an Update on MR Imaging Findings with Recent Developments.
Primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC) are the most common immune-mediated chronic cholestatic liver diseases leading to cirrhosis and liver failure. Although magnetic resonance imaging (MRI) is not a necessary procedure for the diagnosis of PBC, MRI is recommended for monitoring disease progression and early detection of complications. Even though liver cirrho...
متن کاملPrimary Biliary Cirrhosis and Primary Sclerosing Cholangitis: a Review Featuring a Women's Health Perspective
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are two major types of chronic cholestatic liver disease. Each disorder has distinguishing features and variable progression, but both may ultimately result in cirrhosis and hepatic failure. The following offers a review of PBC and PSC, beginning with a general overview of disease etiology, pathogenesis, diagnosis, clinica...
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تاریخ انتشار 2005